Ultrasound-guided Mammotome system in removing benign breast tumors: the correlation between lesion characteristics and biopsy outcome

doi:10.3877/cma.j.issn.1674-0793.2014.01.009

Abstract

Abstract:

Objective

To evaluate the outcome of ultrasound-guided Mammotome system in completely removing benign breast lesions and to find out the clinicopathological factors that might be related with residual lesions with an emphasis on lesion characteristics.

Methods

The date of 1143 female patients with benign-presumed breast lesions from January to December 2012 in our department were retrospectively analyzed. Sonographic follow-up evaluation was performed with a mean interval of four months.

Results

Two thousand three hundred and six benign breast lesions were removed. Follow-up information was available in only 304 patients. 46.7% (142/304) of them did not have residual lesions. Multiple logistic regression analysis indicated that residual lesions at the former sites were more often observed in breasts with multiple, cystic and large lesions.

Conclusions

Besides such factors as needle size and follow-up interval, biopsy outcome is also related with lesion characteristics such as number, nature and size. Unifying the lesion characteristics is of clinical significance for accurately evaluating the biopsy procedure.

Key words: Benign breast lesion, Mammotome, Ultrasound-guided, Residual lesion, Follow-up

Anping Gui, Shien Cui, Feihai Ling. Ultrasound-guided Mammotome system in removing benign breast tumors: the correlation between lesion characteristics and biopsy outcome[J]. Chinese Archives of General Surgery(Electronic Edition), 2014, 08(01): 32-36.

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References 20

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病理		左(n=808)	右(n=806)
良性		?	?
?	纤维腺瘤	294	307
?	纤维增生	273	264
?	纤维囊性变	117	111
?	乳腺腺病	73	75
?	其他	12	11
高危		?	?
?	乳头状瘤	21	22
?	ADH	3	5
?	FEA	5	5
?	乳头状瘤伴ADH	1	0
?	良性叶状肿瘤	4	2
恶性		?	?
?	CC	2	0
?	DCIS	0	1
?	IPC	0	1
?	LCIS	1	0
?	ILC	1	0
?	IDC	1	2

病理		左(n=808)	右(n=806)
良性		?	?
?	纤维腺瘤	294	307
?	纤维增生	273	264
?	纤维囊性变	117	111
?	乳腺腺病	73	75
?	其他	12	11
高危		?	?
?	乳头状瘤	21	22
?	ADH	3	5
?	FEA	5	5
?	乳头状瘤伴ADH	1	0
?	良性叶状肿瘤	4	2
恶性		?	?
?	CC	2	0
?	DCIS	0	1
?	IPC	0	1
?	LCIS	1	0
?	ILC	1	0
?	IDC	1	2

变量		无残留病灶(n=208)	有残留病灶(n=226)	统计值	P值
方向		?	?	?	?
?	左乳	109	113	0.250	0.617
?	右乳	99	113	0.250	0.617
性质		?	?	?	?
?	实性	177	110	?	?
?	囊性	25	89	64.299	<0.001
?	混合^a	6	27	?	?
数量		?	?	?	?
?	1	161	98	?	?
?	2~3	47	110	57.958	<0.001
?	>3	0	18	?	?
边界		?	?	?	?
?	清	171	201	?	?
?	不清	36	15	17.714	<0.001
?	混合^b	1	10	?	?
病理		?	?	?	?
?	良性	198	219	0.842	0.359
?	高危	10	7	0.842	0.359
BI-RADS分级^c		?	?	?	?
?	2	53	43	?	0.014
?	3	107	152	12.417
?	4	47	31	?
?	5	1	0	5.848	<0.001
肿物最大直径(mm)		11.1±4.8	14.6±7.3	5.848	<0.001

变量		无残留病灶(n=208)	有残留病灶(n=226)	统计值	P值
方向		?	?	?	?
?	左乳	109	113	0.250	0.617
?	右乳	99	113	0.250	0.617
性质		?	?	?	?
?	实性	177	110	?	?
?	囊性	25	89	64.299	<0.001
?	混合^a	6	27	?	?
数量		?	?	?	?
?	1	161	98	?	?
?	2~3	47	110	57.958	<0.001
?	>3	0	18	?	?
边界		?	?	?	?
?	清	171	201	?	?
?	不清	36	15	17.714	<0.001
?	混合^b	1	10	?	?
病理		?	?	?	?
?	良性	198	219	0.842	0.359
?	高危	10	7	0.842	0.359
BI-RADS分级^c		?	?	?	?
?	2	53	43	?	0.014
?	3	107	152	12.417
?	4	47	31	?
?	5	1	0	5.848	<0.001
肿物最大直径(mm)		11.1±4.8	14.6±7.3	5.848	<0.001

因素	95%可信区间	P值	OR值
数量	0.226~0.538	<0.001	0.348
性质	0.230~0.546	<0.001	0.354
最大直径	0.883~0.962	<0.001	0.922

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