Optimization of imaging diagnosis for hepatic lesions less than 2 cm

doi:10.3877/cma.j.issn.1674-0793.2017.01.006

Abstract

Abstract:

Objective

To evaluate the value of diagnosis for less than 2 cm liver lesions using contrast-enhanced ultrasound, contrast-enhanced computed tomography, enhanced perfusion imaging and diffusion imaging.

Methods

Fifty-three patients with nodules less than 2 cm underwent standardized contrast-enhanced ultrasound, CT, and MRI scans, respectively. Final diagnosis was determined by pathology or follow-up. Comparative analysis of its diagnostic sensitivity, specificity and accuracy was performed retrospectively.

Results

Based on the pathology or follow-up for patients, we confirmed that there were 27 patients of primary liver cancer, 10 focal nodular hyperplasia, 9 hemangioma, 4 metastatic tumor, 2 liver angioleiomyolipoma, and 1 liver cyst coincidence with infection. Combined with the three diagnosis tests, we found that enhanced perfusion imaging and diffusion imaging had a higher sensitivity, specifity and accuracy (91%, 97%, 93%, respectively) than contrast-enhanced ultrasound, and was significantly prior to computed tomography (P<0.05).

Conclusion

MR enhanced perfusion imaging and diffusion imaging and contrast-enhanced ultrasound has an excellent diagnostic value for liver tumors <2 cm.

Key words: Ultrasonography, Tomography, spiral computed, Perfusion imaging, Magnetic resonance imaging, Liver neoplasms

Jian Wang, Wanguang Zhang. Optimization of imaging diagnosis for hepatic lesions less than 2 cm[J]. Chinese Archives of General Surgery(Electronic Edition), 2017, 11(01): 23-27.

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Figures/Tables 4

References 10

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检查项目	TP	FN	FP	TN	敏感度		特异度		PPV（%）	准确性		NPV（%）
检查项目	TP	FN	FP	TN	%	P值	%	P值	PPV（%）	%	P值	NPV（%）
增强CT	26	10	3	25	72	0.147^a	89	0.639^a	89	71	80	0.144^a
超声造影	31	5	2	26	86	0.466^b	93	0.553^b	94	84	89	0.344^b
PWI+DWI	33	3	1	27	91	0.032^c	97	0.299^c	97	90	93	0.019^c

检查项目	TP	FN	FP	TN	敏感度		特异度		PPV（%）	准确性		NPV（%）
检查项目	TP	FN	FP	TN	%	P值	%	P值	PPV（%）	%	P值	NPV（%）
增强CT	26	10	3	25	72	0.147^a	89	0.639^a	89	71	80	0.144^a
超声造影	31	5	2	26	86	0.466^b	93	0.553^b	94	84	89	0.344^b
PWI+DWI	33	3	1	27	91	0.032^c	97	0.299^c	97	90	93	0.019^c

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