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Chinese Archives of General Surgery(Electronic Edition) ›› 2017, Vol. 11 ›› Issue (05): 340-343. doi: 10.3877/cma.j.issn.1674-0793.2017.05.011

Special Issue:

• Original Article • Previous Articles     Next Articles

Study of SPECT/CT planar and tomography imaging in the diagnosis of postoperative lung metastasesof differentiated thyroid carcinoma

Feng Zhang1, Liangjun Xie1,(), Yudao Chen1, Muhua Cheng1   

  1. 1. Department of Nuclear Medicine, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
  • Received:2017-05-09 Online:2017-10-01 Published:2017-10-01
  • Contact: Liangjun Xie
  • About author:
    Corresponding author: Xie Liangjun, Email:

Abstract:

Objective

To compare the diagnostic values of SPECT/CT planar and tomography imaging in postoperative lung metastases of differentiated thyroid carcinoma.

Methods

Sixty-four cases with suspected postoperative lung metastasis of differentiated thyroid carcinoma from January 2012 to October 2016 were retrospectively analyzed in the Third Affiliated Hospital of Sun Yat-sen University. All patients were given SPECT/CT planar and tomography imaging, and the diagnostic results of SPECT/CT planar and tomography imaging in postoperative lung metastases of differentiated thyroid carcinoma were statistically analyzed.

Results

Among the 64 cases, there were 48 cases of postoperative lung metastases of differentiated thyroid carcinoma, and 16 non pulmonary metastasis. SPECT/CT planar imaging showed lung metastasis in 40 cases, of which 12 were false positive, and non pulmonary metastasis in 24 cases, of which 20 were false negative. SPECT/CT tomographic imaging diagnosed lung metastasis in 52 cases, of which 48 cases were true positive, and non pulmonary metastasis in 12 cases, of which 4 were false positive. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of SPECT/CT tomographic imaging of postoperative lung metastases of differentiated thyroid carcinoma were significantly higher than that of SPECT/CT planar imaging (χ2=12.63, 4.00, 11.14, 3.92, 11.25, P=0.032, 0.033, 0.024, 0.042, 0.013) .

Conclusion

The diagnostic value of SPECT/CT tomography imaging in postoperative lung metastases of differentiated thyroid carcinoma is higher than SPECT/CT planar imaging, and is worthy of promotion in the clinic.

Key words: Differentiated thyroid carcinoma, Lung metastasis, SPECT/CT planar imaging, SPECT/CT tomography

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