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Chinese Archives of General Surgery(Electronic Edition) ›› 2024, Vol. 18 ›› Issue (02): 142-146. doi: 10.3877/cma.j.issn.1674-0793.2024.02.015

• Review • Previous Articles    

Roles of microRNAs in the development, diagnosis and treatment of cholangiocarcinoma

Minchao Zheng1,2, Chenggong Li1,2, Zhiqiang Chen1,2, Zhonghua Shang1,()   

  1. 1. Department of General Surgery, the Second Hospital of Shanxi Medical University, Taiyuan 030000, China
    2. Shanxi Medical University, Taiyuan 030000, China
  • Received:2023-07-12 Online:2024-04-01 Published:2025-03-12
  • Contact: Zhonghua Shang

Abstract:

Cholangiocarcinoma is a malignant tumor originating from biliary epithelium, so that its incidence rate is relatively low, but the fatality rate is high.Most patients are at late stage when they are diagnosed.Even with timely and effective surgical intervention at the time, the prognosis is still unsatisfactory.Early detection, diagnosis, and treatment is essential.This review aims to summarize the role of microRNAs (miRNAs) in the development, diagnosis and treatment of cholangiocarcinoma and provide references for clinical work.

Key words: MicroRNAs, Bile duct neoplasms, Biomarks, tumor, Prognosis

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