Abstract:

Liver transplantation is currently considered as one of the most important methods for the treatment of hepatocelluar carcinoma （HCC）.However， due to the strict standards of liver transplantation，many patients have exceeded the transplantation standards.For such patients， tumor downstaging is undoubtedly an ideal way， which can reduce the tumor load to the transplantation standards， thereby reducing tumor recurrence and improving survival time.There have been many kinds of descending stage treatment for HCC， such as transcatheter arterial chemoembolization （TACE）， transarterial radioembolization（TARE）， hepatic arterial infusion chemotherapy （HAIC）， targeted therapy alone or in combination with immunotherapy.However， there are still some limits for the safety and effectiveness of liver transplantation conversion therapy for HCC.This article provides a brief introduction of the current status of liver transplantation conversion therapy for HCC based on published literature.

Key words: Carcinoma， hepatocellular, Conversion therapy, Liver transplantation