An analysis of the relationship between serum leptin and insulin in patients with primary liver cancer

doi:10.3877/cma.j.issn.1674-0793.2007.03.014

Abstract

Abstract:

Objective

To investigate the role of serum leptin and insulin in the production and progress of primary liver cancer.

Methods

The serum leptin and insulin of 70 primary liver cancer patients were detected by radioimmunoassay and electrochemiluminescence respectively. The relationship between leptin and other values was analyzed.

Results

Serum leptin and insulin levels were significantly higher in primary liver cancer group compared to that in the control group and the BMI of primary liver cancer group was significantly lower than healthy control group.

Conclusion

Leptin and insulin induced the malnutrition in primary liver cancer patients， which may be the risk factors of primary liver cancer.

Key words: Primary liver cancer, Leptin, Insulin

Ming-xin YE, Zheng-ming LEI, Lei YIN. An analysis of the relationship between serum leptin and insulin in patients with primary liver cancer[J]. Chinese Archives of General Surgery(Electronic Edition), 2007, 01(03): 169-171.

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URL: https://zhptwkxwx.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-0793.2007.03.014

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Figures/Tables 2

References 14

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分组	瘦素(ng/ml)	胰岛素(IU/ml)	体重指数（kg/m²）
对照组	5.25±1.70	4.97±1.58	22.8±2.3
肝硬化组	7.50±1.95^*	7.60±1.71^*	21.3±1.9^*
肝癌组	7.67±2.28^*	7.89±4.02^*	21.1±1.6^*

分组	瘦素(ng/ml)	胰岛素(IU/ml)	体重指数（kg/m²）
对照组	5.25±1.70	4.97±1.58	22.8±2.3
肝硬化组	7.50±1.95^*	7.60±1.71^*	21.3±1.9^*
肝癌组	7.67±2.28^*	7.89±4.02^*	21.1±1.6^*

变量名	系数	标准误	Beta	t	P
常数项	-14.852	8.526	-	-5.824	0.000
BMI	0.742	5.248	0.562	5.944	0.000
性别	4.256	1.243	0.237	3.046	0.011
胰岛素	0.945	2.035	0.481	4.527	0.006

变量名	系数	标准误	Beta	t	P
常数项	-14.852	8.526	-	-5.824	0.000
BMI	0.742	5.248	0.562	5.944	0.000
性别	4.256	1.243	0.237	3.046	0.011
胰岛素	0.945	2.035	0.481	4.527	0.006

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