Abstract:

Objective

To investigate the factors affected the prognosis of rectal carcinoma received radical resection,the 3 and 5-year survival rate of reoperation,based on the clinical datum analysis.

Methods

535 patients with rectal carcinoma received radical resection were analyzed retrospectively. The relationship of the clinical-pathological factors with the prognostic factors of reoperation were analyzed using log-rank analysis and the primary risk factors were obtained and multiple analysis was conducted to determinate the independent risk factors.The 3 and 5-year survival rate of reoperation were calculated based on Kaplan-Meier estimate analysis.

Results

All these 535 rectal carcinoma patients received radical resection.Local recurrence (LR)occurred in 53 cases (9.9%). The recurrence occurred 12 (4-54) months postoperatively. Radical reoperation resection were performed in 21 cases,palliative resection in 17 cases,exploration operation in 6 cases and non operation treatment in 9 cases,There were significant difference between the different surgical treatment cases (P＜0.01).The 3- and 5- year survival rates based on Kaplan-Meier estimate analysis were 30.78%, 16.68%.

Conclusions

Whether the recurrence lesion can be radically resected is an independent factor related to the prognosis and the recurrent patients whose lesion may be radically resected presents a good prognosis.If permitted,surgical resection may be performed actively for LR patients.

Key words: Rectaltumor, Localrecurrence, Prognosis