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Chinese Archives of General Surgery(Electronic Edition) ›› 2009, Vol. 03 ›› Issue (05): 38-40. doi: 10.3877/cma.j.issn.1674-0793.2009.05.012

• Original Articles • Previous Articles     Next Articles

Role of continuous blood purification on treatment of hyperosmosis with unconsciousness after liver transplantation

Hui-min YI1, Gen-shu WANG1, Shu-hong YI1, Ying-hua CHEN1, Chang-jie CAI1, Yang YANG1, Min-qiang LU1, Gui-hua CHEN1,()   

  1. 1.Liver transplantation center, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China
  • Received:2009-05-21 Online:2009-10-01 Published:2024-12-01
  • Contact: Gui-hua CHEN

Abstract:

Objective

To investigate the role of continuous blood purification(CBP)on treatment of hyperosmosis with unconsciousness after liver transplantation.

Methods

Twenty-four cases of post liver transplantation patients with hyperosmosis and unconsciousness were retrospectively analyzed.Ten patients were treated by conventional method including hypoosmotic fluid infusion and positive balance of fluid (conventional group).Forteen patients were treated with CBP(CBP group).

Results

The hyperosmosis and unconsciousness of 4 patients were cured in conventional group. The hyperosmosis of all patients in CBP group was normalized with the decrease of serum sodium,BUN and critinine to normal level.And 11 (78.6%)patients waked after the treatment of CBP. The GLASGOW score was improved to 14-15. The patients who were still unconscious were complicated with pulmonary infection or MODS and the prognosis were poor.

Conclusion

CBP may cure the hyperosmosis with unconsciousness in liver transplantation patients by the normalization of serum osmotic pressure and electrolyte balance to improve the prognosis of liver transplantation.

Key words: Hyperosmosis;Liver transplantation;Encephalopathies metabolic;Hemofiltration

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