To explore the efficacy and safety of enhanced recovery after surgery (ERAS) in perioperative period of laparoscopic repair for gastroduodenal perforation.

The clinical data of one hundred and thirty-two patients with giant upper gastrointestinal perforation treated by laparoscopy from February 2015 to February 2019 in Inner Mongolia Autonomous Region People’s Hospital were retrospectively analyzed. According to whether ERAS was combined with perioperative treatment or not, they were divided into ERAS group (72 cases) and the traditional group (60 cases). The postoperative recovery was compared between the two groups.

Compared with the traditional group, the recovery time of gastrointestinal function, the first normal eating time and hospitalization time of the patients in ERAS group were significantly shorter, and the negative mood during the perioperative period, the level of C-reactive protein and the incidence of complications after the operation were also significantly lower, and the pain after the operation was significantly lighter (P<0.05).

The combination of ERAS concept and laparoscopic technique can effectively promote the perioperative rehabilitation of patients with giant upper gastrointestinal perforation and shorten their hospital stay.