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Chinese Archives of General Surgery(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (03): 183-187. doi: 10.3877/cma.j.issn.1674-0793.2025.03.007

• Review • Previous Articles     Next Articles

Application and research progress of arginine and glutamine in gastric cancer treatment

Shigong Chen1, Wenjing Wang2, Xiulan Li3, Bo Long1, Zuoyi Jiao1,()   

  1. 1. Department of General Surgery, the Second Hospital of Lanzhou University, Lanzhou 730030, China
    2. Department of Cardiology, Gansu Provincial Central Hospital, Lanzhou 730030, China
    3. Center of Digestive Endoscopy, Hunan Provincial People’s Hospital,Hunan Normal University, Changsha 410000, China
  • Received:2024-11-24 Online:2025-06-01 Published:2025-06-20
  • Contact: Zuoyi Jiao

Abstract:

Gastric cancer is one kind of malignant tumors with high global incidence and mortality rates.Patients with gastric cancer often experience malnutrition, which adversely affects postoperative recovery, chemotherapy tolerance, and overall prognosis.In recent years, immunonutrition, as a nutritional intervention method aimed at enhancing immune function, has gained widespread attention.Immunonutrition not only improves nutritional status, but also regulates immune function, reduces inflammatory responses,promotes wound healing and intestinal repair, and aids in the treatment of gastric cancer.This paper systematically reviews the application of arginine and glutamine in the treatment of gastric cancer and their impact on patients’ prognosis, trying to provide references for clinical practice and research while exploring future research directions.

Key words: Stomach neoplasms, Arginine, Glutamine, Surgery, Chemotherapy

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